Lotzorai is a comune (municipality) in the Province of Ogliastra in the Italian region Sardinia, located about 100 km northeast of Cagliari and about 4 km northeast of Tortolì. As of 31 December 2004, it had a population of 2,153 and an area of 16.8 km².
Lotzorai borders the following municipalities: Baunei, Girasole, Talana, Tortolì, Triei, Villagrande Strisaili.